A case of anti-BP180-type mucous membrane pemphigoid difficult to distinguish from bullous pemphigoid
نویسندگان
چکیده
منابع مشابه
Localized genital bullous pemphigoid; A case report
Bullous pemphigoid (BP) is an autoimmune bullous disorder with urticarial pruritic papules and plaques and tense bullae in flexural surfaces of body. The localized form of the disease is a rare variant which can be triggered by different stimuli. Hereunder, we report a patient with the local type involving genitalia without any triggering factors.
متن کاملMucous membrane pemphigoid
Introduction Identifying risk factors for leprosy reactions can preempt clinicians to initiate prompt treatment to prevent associated morbidities. Thus, a retrospective study was done to elucidate the risk factors among 44 newly diagnosed leprosy patients in Sarawak General Hospital from 1993 to 2007. Materials and methods Case folders were searched for demographic data, clinical characteristic...
متن کاملBullous Pemphigoid, Mucous Membrane Pemphigoid and Pemphigus Vulgaris: An Update on Pathobiology
Pemphigoid and pemphigus vulgaris (PV) are autoimmune diseases that cause potentially debilitating erosions and blistering of the skin and/or mucous membranes. In bullous pemphigoid (BP), autoantibodies target components of the basement membrane zone (BMZ), most importantly the hemidesmosomal proteins, BP180 and BP230. Research efforts have uncovered some of the complex mechanisms that cause th...
متن کاملBP230- and BP180-specific auto-antibodies in bullous pemphigoid.
Bullous pemphigoid is a subepidermal blistering disease associated with auto-antibodies (auto-ab) to BP180 and BP230. We developed ELISAs utilizing baculovirus-encoded recombinant proteins of BP230 and BP180 and studied their diagnostic and prognostic values by assessing the profile of the auto-ab response in 127 patients with BP. 39 patients had focal involvement, whereas 88 had generalized di...
متن کاملBP180 Is Critical in the Autoimmunity of Bullous Pemphigoid
Bullous pemphigoid (BP) is by far the most common autoimmune blistering dermatosis that mainly occurs in the elderly. The BP180 is a transmembrane glycoprotein, which is highly immunodominant in BP. The structure and location of BP180 indicate that it is a significant autoantigen and plays a key role in blister formation. Autoantibodies from BP patients react with BP180, which leads to its degr...
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ژورنال
عنوان ژورنال: Japanese Journal of Oral and Maxillofacial Surgery
سال: 2012
ISSN: 0021-5163,2186-1579
DOI: 10.5794/jjoms.58.297